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Lilopristone

Lilopristone (ZK98734) is a progesterone antagonist with a potential to induce menstruation, inhibit nidation, and terminate pregnancy. Lilopristone blocks progesterone action at the endometrium as well as decreases progesterone bioavailability, and can be utilized in antifertility research[1].

Product Specifications

CAS Number

[97747-88-1]

Product Name Alternative

ZK98734

UNSPSC

12352005

Target

Progesterone Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/lilopristone.html

Smiles

C[C@@]12[C@](CC[C@@]2(O)/C=C\CO)([H])[C@@]3([H])C([C@@H](C4=CC=C(C=C4)N(C)C)C1)=C5C(CC3)=CC(CC5)=O

Molecular Formula

C29H37NO3

Molecular Weight

447.61

References & Citations

[1]Puri CP, et al. Effects of progesterone antagonist, lilopristone (ZK 98.734), on induction of menstruation, inhibition of nidation, and termination of pregnancy in bonnet monkeys. Biol Reprod. 1990 Sep;43 (3) :437-43.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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