3-Methoxybenzamide

3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells[1]. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum) [2].

Product Specifications

CAS Number

[5813-86-5]

Product Name Alternative

3-MBA

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; PARP

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/3-methoxybenzamide.html

Purity

99.40

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N)C1=CC=CC(OC)=C1

Molecular Formula

C8H9NO2

Molecular Weight

151.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Y Ohashi, et al. The lethal effect of a benzamide derivative, 3-methoxybenzamide, can be suppressed by mutations within a cell division gene, ftsZ, in Bacillus subtilis. J Bacteriol. 1999 Feb;181 (4) :1348-51.|[2]Venkateswari J. Chetty, et al. Poly (ADP-ribose) polymerase inhibitor 3-methoxybenzamide enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum) . In Vitro Cellular & Developmental Biology - Plant (2020) .