DpC
DpC is an anti-tumor agent. DpC inhibits cancer cell proliferation (IC50: 0.007-0.096 μM) . DpC synergizes with multiple anti-cancer therapeutics[1].
Product Specifications
Product Name Alternative
Adonitol-3-13C; Adonite-3-13C,Adonitol-5-13C; Adonite-5-13C
UNSPSC
12352005
Hazard Statement
H301
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dpc.html
Purity
98.73
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
S=C(N/N=C(C1=NC=CC=C1)\C2=NC=CC=C2)N(C3CCCCC3)C
Molecular Formula
C19H23N5S
Molecular Weight
353.48
Precautions
H301
References & Citations
[1]Dharmasivam M, et al. The thiosemicarbazone, DpC, broadly synergizes with multiple anti-cancer therapeutics and demonstrates temperature- and energy-dependent uptake by tumor cells. Biochim Biophys Acta Gen Subj. 2022 Aug;1866 (8) :130152.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114243/DpC-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114243/DpC-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Phase 4
CAS Number
[1382469-39-7]
Available Sizes
Curated Selection
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