Cathepsin K Substrate II Fluorogenic

<strong>Cathepsin K Substrate II Fluorogenic</strong>_x000D_ <strong>Catalog number:</strong> B2014038_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 918.91 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> Cathepsin K Substrate II, Fluorogenic_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Lecaille F, Chazeirat T, Bojarski KK, Renault J, Saidi A, Prasad VGNV, Samsonov S, Lalmanach G. Rat cathepsin K: Enzymatic specificity and regulation of its collagenolytic activity Biochim Biophys Acta Proteins Proteom. 2020 Feb;1868(2):140318._x000D_ 2: Mukherjee K, Chattopadhyay N. Pharmacological inhibition of cathepsin K: A promising novel approach for postmenopausal osteoporosis therapy Biochem Pharmacol. 2016 Oct 1;117:10-9._x000D_ 3: Li Z, Hou WS, Escalante-Torres CR, Gelb BD, Bromme D. Collagenase activity of cathepsin K depends on complex formation with chondroitin sulfate J Biol Chem. 2002 Aug 9;277(32):28669-76._x000D_ 4: Hwang HS, Chung HS. Preparation of active recombinant cathepsin K expressed in bacteria as inclusion body Protein Expr Purif. 2002 Aug;25(3):541-6._x000D_ 5: Li Z, Hou WS, Brmme D. Collagenolytic activity of cathepsin K is specifically modulated by cartilage-resident chondroitin sulfates Biochemistry. 2000 Jan 25;39(3):529-36._x000D_ 6: Lecaille F, Chowdhury S, Purisima E, Brmme D, Lalmanach G. The S2 subsites of cathepsins K and L and their contribution to collagen degradation Protein Sci. 2007 Apr;16(4):662-70._x000D_ 7: Vasiljeva O, Reinheckel T, Peters C, Turk D, Turk V, Turk B. Emerging roles of cysteine cathepsins in disease and their potential as drug targets Curr Pharm Des. 2007;13(4):387-403._x000D_ 8: de Melo Pereira D, Davison N, Habibovi P. Human osteoclast formation and resorptive function on biomineralized collagen Bioact Mater. 2021 Jul 15;8:241-252._x000D_ 9: de Maat S, Clark CC, Boertien M, Parr N, Sanrattana W, Hofman ZLM, Maas C. Factor XII truncation accelerates activation in solution J Thromb Haemost. 2019 Jan;17(1):183-194._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20045715">10: Oliveira M, Torquato RJ, Alves MF, Juliano MA, Brmme D, Barros NM, Carmona AK. Improvement of cathepsin S detection using a designed FRET peptide based on putative natural substrates Peptides. 2010 Apr;31(4):562-7. </a>_x000D_ _x000D_ <strong>Products Related to Cathepsin K Substrate II Fluorogenic can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>