What is the catalog number for MALT1 Antibody?

The catalog number for MALT1 Antibody is orb749401.

What sizes are available for MALT1 Antibody?

MALT1 Antibody is available in the following size(s): 20 µg, 100 µg.

How many pack sizes does MALT1 Antibody come in?

MALT1 Antibody is available in 2 different pack sizes.

Is MALT1 Antibody in stock?

MALT1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

MALT1 Antibody

Mucosa associated lymphoid tissue lymphoma translocation gene 1 is found in extranodal low-grade B cell lymphomas. It encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of the MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18) (q21; q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclearï¿1⁄2Bcl10, which mediates the oligomerization and activation of a caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.

Product Specifications

Reactivity

Human

Immunogen

A recombinant fragment (aa 701-808) was used as the immunogen for this antibody.

Clonality

Monoclonal

Clone

MT1/410

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Protein G purified monoclonal antibody

Dilution

Western blot: 1-2ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT (1) (2)

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.