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CD98 Antibody / SLC3A2

CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.

Product Specifications

Reactivity

Human

Immunogen

The Molt-13 T cell line was used as the immunogen for this CD98 antibody.

Clonality

Monoclonal

Clone

UM7F8

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Protein G purified CD98 antibody

Dilution

Comitogenic with soluble anti-CD2 and immobilized anti-CD3 mAbs, Flow cytometry: 0.5-1ug/10^6 cells, Immunofluorescence: 0.5-1ug/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD98 antibody to be titered up or down for optimal performance.

Tested Applications

FACS, Functional Studies, IF

Host or Source

Mouse

Preservative

0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide

Isotype

Mouse IgG1, kappa

Available Sizes

Frequently Asked Questions

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