What is the catalog number for CD47 Antibody / IAP?

The catalog number for CD47 Antibody / IAP is orb749334.

What sizes are available for CD47 Antibody / IAP?

CD47 Antibody / IAP is available in the following size(s): 20 µg, 100 µg.

How many pack sizes does CD47 Antibody / IAP come in?

CD47 Antibody / IAP is available in 2 different pack sizes.

Is CD47 Antibody / IAP in stock?

CD47 Antibody / IAP is currently made to order / not held in immediate stock. Contact us for lead time.

CD47 Antibody / IAP

This antibody reacts with the Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is an ~ 50kDa glycoprotein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Product Specifications

Reactivity

Human

Immunogen

Intact CD47 purified from placenta was used as the immunogen for this antibody.

Clonality

Monoclonal

Clone

B6H12.2

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation; Cell Biology

Purification

Protein G affinity chromatography

Dilution

Western blot: 1-2ug/ml, Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2ug/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.