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RUNX3 Antibody

The Runt family of transcription factors is involved in both normal cell development and carcinogenesis. Runt-related transcription factor 3 has been shown to be a tumor suppressor. Hypermethylation and mislocalization of the protein to the cytoplasm leads to low levels of RUNX3 and increased proliferation of breast and gastric tumor cells.

Product Specifications

Reactivity

Human

Immunogen

A RUNX3 recombinant protein fragment was used as the immunogen for this antibody.

Clonality

Monoclonal

Clone

RNX864

Conjugation

Unconjugated

Purification

Protein G Affinity Chromatography

Dilution

Western blot: 2-4ug/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Provided assay concentrations are suggestions only, RUNX3 antibody titration may be required for optimal results.

Tested Applications

WB

Host or Source

Mouse

Preservative

0.5 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide

Isotype

Mouse IgG1, kappa

Available Sizes

Frequently Asked Questions

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