Exportin 4 Antibody
Importins and exportins are transport receptors carrying cargo molecules into and out of the nucleus. Exportin 4 is a member of the Importin B superfamily of RanGTP-binding proteins. Its homology to other family members is restricted to its N-terminal RanGTP-binding motif. Exportin 4 is a nuclear export receptor for eIF-5A, a protein involved in the cellular stress response, functioning as a regulator of p53-mediated and TNF-alpha-mediated apoptosis.
Product Specifications
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant protein fragment from the C-terminal portion of Exportin 4 was used as the immunogen for this antibody.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Protein A affinity chromatography
Dilution
Western blot: 1-3ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.5 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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