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CRHR2 Antibody

CHCR2, or Corticotropin releasing hormone receptor 2, is a receptor for CRH (corticotropin-releasing hormone), a neurotransmitter secreted by the hypothalamus in response to stress. There are three major isoforms of CHCR2: alpha, beta and gamma, differing in their N-terminus amino acid sequence. Isoform beta and gamma are expressed in the brain, with gamma expression highest in the septum and hippocampus, while alpha is expressed in the peripheral tissues of the brain.

Product Specifications

UniProt

Q13324

Reactivity

Human, Mouse, Rat

Immunogen

A recombinant protein fragment from the N-terminal portion of human CRHR2 was used as the immunogen for this antibody (1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Epigenetics, GPCR, Neuroscience, Signaling Pathways

Purification

Protein A affinity chromatography

Dilution

Western blot: 0.5-2ug/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Provided assay concentrations are suggestions only, CRHR2 antibody titration may be required for optimal results.1. This antibody will detect the alpha (411 AA), beta (438 AA) and gamma (397 AA) isoforms of CRHR2.

Tested Applications

WB

Host or Source

Rabbit

Preservative

0.5 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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