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TARBP2 Antibody

TARBP2 (TAR (HIV-1) RNA binding protein 2), along with Dicer and Argonaute-2, is part of the RISC (RNA induced silencing complex) . As part of the RISC, TRBP2 is important in viral defense. Dicer cleaves dsRNA into siRNA. Through TRBP2-Dicer interaction, the siRNA template is loaded onto Argonaute-2, which cleaves encountered viral mRNA strands complementary to the loaded siRNA base-pair sequence.

Product Specifications

Reactivity

Human, Mouse, Primate

Immunogen

A recombinant protein fragment within the C-terminal region of TARBP2 was used as the immunogen for this antibody.

Clonality

Polyclonal

Conjugation

Unconjugated

Purification

Protein A Affinity Chromatography

Dilution

Western blot: 5-10ug/ml

References & Citations

N Shree, S Meruvu, MH Park, M Choudhury High-Fat-High-Fructose Diet Elicits Brown Adipocyte Dysfunction through miRNA-103 Induced miRNA Biogenesis Pathway Obesities, (2024)

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

Tested Applications

WB

Host or Source

Rabbit

Preservative

0.5 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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