NKIRAS1 Antibody
NKIRAS1 is part of the Ras family and GTPase superfamily of proteins. Unlike other family members which have a glycine and glutamine residue at positions 13 and 65, NKIRAS1 (and 2) has leucines in these positions.NKIRAS1 is a regulator of NF-kB activity via its inhibition of IkB (NFKBIB) degradation. IkB complexes with NF-kB, preventing nuclear translocation and subsequent signaling. By preventing or reducing IkB degradation, NKIRAS1 blocks NF-kB signaling activity.
Product Specifications
UniProt
Q9NYS0
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant protein fragment from the central region of NKIRAS1 was used as the immunogen for this antibody.
Clonality
Monoclonal
Clone
NRAS285
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
Protein G purified antibody
Dilution
Western blot: 5-10ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Provided assay concentrations are suggestions only, NKIRAS1 antibody titration may be required for optimal results.
Tested Applications
WB
Host or Source
Mouse
Preservative
0.5 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Mouse IgG1, kappa
Available Sizes
Frequently Asked Questions
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