SGK1 Antibody
SGK1 (Serine/threonine-protein kinase 1) is a member of a serine/threonine subfamily of kinases. This kinase is involved in a wide variety of cellular functions including cell growth, survival and migration as well as a wide variety of cellular processes including transcription (Foxo3A, b-catenin, NF-kB, and p53), stress response and apoptosis. SGK1 also participates in neuronal function. Expression of SGK1 is stimulated by amphetamine, LSD and neuronal injury, it stimulates dendrite growth, is important in long term memory, fear-conditioning/spatial/novel object recognition learning and is likely involved in the pathophysiology of Alzheimer's disease.
Product Specifications
Reactivity
Human
Immunogen
A recombinant protein fragment from the C-terminal region of human SGK1 was used as the immunogen for this antibody.
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Protein A affinity chromatography
Dilution
Western blot: 1-3ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.5 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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