PACS-1 Antibody
PACS proteins are involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. PACS-1, or Phosphofurin acidic cluster sorting protein 1, is involved in protein sorting and ion channel trafficking. It directs the trans-Golgi network (TGN) localization of furin and M6PR (Mannose 6-phosphate receptor) . PACS-1 also mediates the binding of VAMP4, a TGN-to-endosome transport protein, to AP-1.
Product Specifications
Reactivity
Human, Mouse
Immunogen
A recombinant protein fragment from the intermal portion of human PACS-1 was used as the immunogen for this antibody.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Protein A affinity chromatography
Dilution
Western blot: 1-3ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.5 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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