Polycarbophil
Polycarbophil is an orally active hydrophilic polymer. Polycarbophil achieves bioadhesion through hydrogen bonding between carboxyl groups and mucosal surfaces, and prolongs compound retention time and regulates compound release through swelling properties. Polycarbophil relieves constipation and diarrhea[1][2][3].
Product Specifications
CAS Number
9003-97-8
UNSPSC
12352100
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/polycarbophil.html
Solubility
10 mM in DMSO
Smiles
[Polycarbophil]
References & Citations
[1]Zhu Z, et al. The development of polycarbophil as a bioadhesive material in pharmacy. asian journal of pharmaceutical sciences, 2013, 8 (4) : 218-227.|[2]Grabnar I, et al. Influence of chitosan and polycarbophil on permeation of a model hydrophilic drug into the urinary bladder wall. Int J Pharm. 2003 Apr 30;256 (1-2) :167-73. |[3]Saito T, et al. Laxative and anti-diarrheal activity of polycarbophil in mice and rats. Jpn J Pharmacol. 2002 Jun;89 (2) :133-41.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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