Amauromine
Amauromine is a peripheral selective cannabinoid receptor type 1 (CB1) receptor antagonist with Ki and Kb values of 178 nM and 66.6 nM, respectively[1].
Product Specifications
CAS Number
88360-87-6
UNSPSC
12352005
Hazard Statement
H302+H312+H332
Target
Cannabinoid Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/amauromine.html
Solubility
10 mM in DMSO
Smiles
C=CC(C)([C@]12[C@](NC3=CC=CC=C23)([H])N4[C@@](C(N5[C@](C[C@]6(C(C)(C)C=C)[C@@]5([H])NC7=CC=CC=C67)([H])C4=O)=O)([H])C1)C
Molecular Formula
C32H36N4O2
Molecular Weight
508.65
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
References & Citations
[1]Elsebai MF, et al. Identification of a Potent and Selective Cannabinoid CB1 Receptor Antagonist from Auxarthron reticulatum. ACS Med Chem Lett. 2011 Sep 17;2 (11) :866-9.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CB1
Available Sizes
Frequently Asked Questions
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