NEU617
NEU617 is an anti-parasite agent. NEU617 inhibits the proliferation for the HAT (human African trypanosomiasis) pathogen (EC50: 42 nM for Trypanosoma brucei, 1.8 μM for T. cruzi). NEU617 is a derivative of Lapatinib.
Product Specifications
CAS Number
1432450-82-2
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/neu617.html
Smiles
FC1=CC(COC2=CC=C(NC3=C4C=C(C5=CC=CC(N6CCOCC6)=C5)C=CC4=NC=N3)C=C2Cl)=CC=C1
Molecular Formula
C31H26ClFN4O2
Molecular Weight
541.02
References & Citations
[1]Devine W, et al. Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery. J Med Chem. 2015 Jul 23;58 (14) :5522-37.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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