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1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is an AP-1 inhibitor which can be found in Cordyceps bassiana. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid downregulates the expression of COX-2. 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid can be used for the study of atopic dermatitis[1][2].

Product Specifications

CAS Number

3719-45-7

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

AP-1; COX

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/1-methyl-6-oxo-1-6-dihydropyridine-3-carboxylic-acid.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C(C=C1)=CN(C)C1=O)O

Molecular Formula

C7H7NO3

Molecular Weight

153.14

Precautions

H315, H319, H335

References & Citations

[1]Suh W, et al. Chemical Constituents Identified from Fruit Body of Cordyceps bassiana and Their Anti-Inflammatory Activity. Biomol Ther (Seoul) . 2017 Mar 1;25 (2) :165-170. |[2]Brüggemann Y, et al. JNK kinase regulates phosphorylation of HCoV-229E nucleocapsid protein. Npj Viruses. 2025 Sep 18;3 (1) :69.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

COX-2

Available Sizes

Frequently Asked Questions

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