Ro 3-1314

Ro 3-1314 (9a,12a-Octadecadiynoic acid) is a plant lipoxygenase inhibitor. Ro 3-1314 is a linoleic acid metabolism inhibitor. Ro 3-1314 stimulates the antigen-induced contraction of guinea-pig tracheal spirals and the immunological release of slow reacting substance of anaphylaxis (SRS-A) from actively sensitized guinea-pig lung fragments[1].

Product Specifications

CAS Number

[2012-14-8]

Product Name Alternative

9a,12a-Octadecadiynoic acid

UNSPSC

12352211

Target

Lipoxygenase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ro-3-1314.html

Purity

99.0

Solubility

10 mM in DMSO

Smiles

O=C(CCCCCCCC#CCC#CCCCCC)O

Molecular Formula

C18H28O2

Molecular Weight

276.41

References & Citations

[1]M Hitchcock, et al. Arachidonic acid metabolism and modulation of in vitro anaphylaxis by 5,8,11,14-eicosatetraynoic acid and 9a,12a-octadecadiynoic acid. Br J Pharmacol. 1981 Apr;72 (4) :689-95.