Docosahexaenoic acid-d5
Docosahexaenoic acid-d5 is the deuterium labeled Docosahexaenoic Acid. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.
Product Specifications
CAS Number
1197205-71-2
Product Name Alternative
DHA-d5; Cervonic acid-d5
UNSPSC
12352211
Hazard Statement
H225, H319
Target
Endogenous Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Concentration
1.50 mM * 2 mL in Ethanol
Purity
99.71
Solubility
10 mM in DMSO|DMF : ≥ 50mg/mL|DMSO : ≥ 50mg/mL|Ethanol : ≥ 50mg/mL
Smiles
[2H]C([2H])(C([2H])(/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O)[2H])[2H]
Molecular Formula
C22H27D5O2
Molecular Weight
333.52
Precautions
H225, H319
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Horrocks LA, et al. Health benefits of docosahexaenoic acid (DHA) . Pharmacol Res. 1999 Sep;40 (3) :211-25.|[3]Gharami K, et al. Essential role of docosahexaenoic acid towards development of a smarter brain. Neurochem Int. 2015 Oct;89:51-62.|[4]Lengqvist J, et al. Polyunsaturated fatty acids including docosahexaenoic and arachidonic acid bind to the retinoid Xreceptor alpha ligand-binding domain. Mol Cell Proteomics. 2004 Jul;3 (7) :692-703.|[5]Gamoh S, et al. Chronic administration of docosahexaenoic acid improves reference memory-related learning ability in young rats. Neuroscience. 1999;93 (1) :237-41.|[6]Ozsoy O, et al. The influence and the mechanism of docosahexaenoic acid on a mouse model of Parkinson's disease. Neurochem Int. 2011 Oct;59 (5) :664-70.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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