SKF-82958 (hydrobromide)
SKF-82958 ((±) -SKF 82958) hydrobromide is a dopamine D1 receptor full agonist (K0.5=4 nM), displays selective for D1 over D2 receptors (K0.5=73 nM) . SKF-82958 hydrobromide induces dopamine D1 receptor-dependent adenylate cyclase activity in rat striatal membranes (EC50=491 nM) [1].
Product Specifications
CAS Number
74115-01-8
Product Name Alternative
(±) -SKF-82958 (hydrobromide) ; Chloro-APB (hydrobromide)
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/SKF-82958-hydrobromide.html
Purity
99.53
Solubility
DMSO : ≥ 100 mg/mL
Smiles
OC1=C(O)C=C2C(C3=CC=CC=C3)CN(CC=C)CCC2=C1Cl.[H]Br
Molecular Formula
C19H21BrClNO2
Molecular Weight
410.73
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D1 Receptor
Available Sizes
Frequently Asked Questions
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