PKMYT1-IN-1
PKMYT1-IN-1 (Compound 1) is an inhibitor for membrane-associated tyrosine and threonine kinase (PKMYT1), with an IC50 of 8.8 nM. PKMYT1-IN-1 inhibits proliferation of tumor cell HCC1569 with IC50 of 42 nM[1].
Product Specifications
CAS Number
[3033609-83-2]
UNSPSC
12352005
Target
Wee1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pkmyt1-in-1.html
Purity
99.2400
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC=C(C(C)=C1N2C(N)=C3C(NC4=C(C5=NC=NC2=C53)C=CC=C4)=O)O
Molecular Formula
C21H17N5O2
Molecular Weight
371.39
References & Citations
[1]Zhu D, et al., Membrane-associated tyrosine and threonine kinase inhibitor and use thereof. WO2024061343A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PKMYT1
Available Sizes
Curated Selection
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