Human Immunoglobulin G4-Fc Antibody Conjugated to Biotin

<strong>Human Immunoglobulin G4-Fc Antibody Conjugated to Biotin</strong>_x000D_ <strong>Catalog number:</strong> B2015742_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Human Immunoglobulin G4-Fc Antibody Conjugated to Biotin_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Rispens T, Leeuwen Av, Vennegoor A, Killestein J, Aalberse RC, Wolbink GJ, Aarden LA. Measurement of serum levels of natalizumab, an immunoglobulin G4 therapeutic monoclonal antibody Anal Biochem. 2011 Apr 15;411(2):271-6._x000D_ 2: Tam SH, McCarthy SG, Armstrong AA, Somani S, Wu SJ, Liu X, Gervais A, Ernst R, Saro D, Decker R, Luo J, Gilliland GL, Chiu ML, Scallon BJ. Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality Antibodies (Basel). 2017 Sep 1;6(3):12._x000D_ 3: Dumet C, Pottier J, Gouilleux-Gruart V, Watier H. Insights into the IgG heavy chain engineering patent landscape as applied to IgG4 antibody development MAbs. 2019 Nov-Dec;11(8):1341-1350._x000D_ 4: Ugamraj HS, Dang K, Ouisse LH, Buelow B, Chini EN, Castello G, Allison J, Clarke SC, Davison LM, Buelow R, Deng R, Iyer S, Schellenberger U, Manika SN, Bijpuria S, Musnier A, Poupon A, Cuturi MC, van Schooten W, Dalvi P. TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity MAbs. 2022 Jan-Dec;14(1):2095949._x000D_ 5: Ji ZX, Chen YN, Zhang YR, Yang YX, Wang CR, Han SY. [Expression of recombinant human IFNa-2b/IgG4 Fc fusion protein in a baculovirus insect cell system] Zhonghua Gan Zang Bing Za Zhi. 2012 Aug;20(8):617-20._x000D_ 6: Jimeno L, Lombardero M, Carreira J, Moscoso Del Prado J. Presence of IgG4 on the membrane of human basophils. Histamine release is induced by monoclonal antibodies directed against the Fab but not the Fc region of the IgG4 molecule Clin Exp Allergy. 1992 Nov;22(11):1007-14._x000D_ 7: Zhang W, Quan Y, Ma X, Zeng L, Li J, Chen S, Su M, Hong L, Li P, Wang H, Xu Q, Zhao C, Zhu X, Geng Y, Yan X, Fang Z, Chen M, Tian D, Su M, Chen X, Gu J. Synergistic effect of glutathione and IgG4 in immune evasion and the implication for cancer immunotherapy Redox Biol. 2023 Apr;60:102608._x000D_ 8: Svilenov HL, Sacherl J, Reiter A, Wolff LS, Cheng CC, Stern M, Grass V, Feuerherd M, Wachs FP, Simonavicius N, Pippig S, Wolschin F, Keppler OT, Buchner J, Brockmeyer C, Protzer U. Picomolar inhibition of SARS-CoV-2 variants of concern by an engineered ACE2-IgG4-Fc fusion protein Antiviral Res. 2021 Dec;196:105197._x000D_ 9: Zhang T, Song X, Xu L, Ma J, Zhang Y, Gong W, Zhang Y, Zhou X, Wang Z, Wang Y, Shi Y, Bai H, Liu N, Yang X, Cui X, Cao Y, Liu Q, Song J, Li Y, Tang Z, Guo M, Wang L, Li K. The binding of an anti-PD-1 antibody to FcγRΙ has a profound impact on its biological functions Cancer Immunol Immunother. 2018 Jul;67(7):1079-1090._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32056048">10: Li X, Wang M, Zhang X, Liu C, Xiang H, Huang M, Ma Y, Gao X, Jiang L, Liu X, Li B, Hou Y, Zhang X, Yang S, Yang N. The novel llama-human chimeric antibody has potent effect in lowering LDL-c levels in hPCSK9 transgenic rats Clin Transl Med. 2020 Feb 13;9(1):16. </a>_x000D_ _x000D_ <strong>Products Related to Human Immunoglobulin G4-Fc Antibody Conjugated to Biotin can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>