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(R) - (-) -O-Desmethyl Venlafaxine-d6

(R) - (-) -O-Desmethyl Venlafaxine-d6 is the deuterium labeled (R) - (-) -O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].

Product Specifications

CAS Number

1062609-96-4

UNSPSC

12352005

Target

Drug Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Solubility

10 mM in DMSO

Smiles

OC1([C@H](C2=CC=C(O)C=C2)CN(C([2H])([2H])[2H])C([2H])([2H])[2H])CCCCC1

Molecular Formula

C16H19D6NO2

Molecular Weight

269.41

References & Citations

[1]Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28.|[2]F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25 (6) :871-80.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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