FOXP3 Antibody / Scurfin

The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.

Product Specifications

CAS Number

9000-83-3

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

Q9BZS1

Host

Rabbit

Reactivity

Human

Immunogen

A recombinant partial protein sequence (within amino acids 300-431) from the human protein was used as the immunogen for the FOXP3 antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG κ

Clone

FOXP3/8277R

Type

Recombinant

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Aliquot the FOXP3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This FOXP3 antibody is available for research use only.

Storage Conditions

Aliquot the FOXP3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the FOXP3 antibody should be determined by the researcher.

Location

Nucleus, Cytoplasm

Image Legend

IHC staining of FFPE human tonsil tissue with FOXP3 antibody (clone FOXP3/8277R) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.