DsDNA Antibody / Double Stranded DNA
This mAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This mAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells. Double Stranded deoxyribonucleic acid (ds DNA) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Not Applicable
Host
Rabbit
Reactivity
Human
Immunogen
Burkitt's cell nuclei were used as the immunogen for the dsDNA antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
DSD/8204R
Type
Recombinant
Applications
IHC-P
Purity
Protein A affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the dsDNA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This dsDNA antibody is available for research use only.
Storage Conditions
Aliquot the dsDNA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the dsDNA antibody should be determined by the researcher.
Location
Nucleus
Image Legend
Frequently Asked Questions
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