Prolactin-Induced Protein Antibody / PIP / GCDFP-15

It recognizes a protein of 15kDa, identified as Prolactin-Induced Protein (PIP), also called Gross cystic disease fluid protein 15 (GCDFP-15) . It is a major protein component of benign breast gross cysts. It is a known marker of breast cancer, as it is found in approximately 50% of all breast cancer specimens. Prolactin inducible protein is a prolactin and androgen-controlled protein. This antibody is useful in the identification of metastatic breast carcinoma, or fluid analysis.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

P12273

Host

Mouse

Reactivity

Human

Immunogen

A recombinant partial protein sequence (within amino acids 41-146) from the human protein was used as the immunogen for the Prolactin-Induced Protein antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

PIP/7477

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Aliquot the Prolactin-Induced Protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Prolactin-Induced Protein antibody is available for research use only.

Storage Conditions

Aliquot the Prolactin-Induced Protein antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the Prolactin-Induced Protein antibody should be determined by the researcher.

Location

Cytoplasm, Secreted

Image Legend

IHC staining of FFPE human breast carcinoma tissue with Prolactin-Induced Protein antibody (clone PIP/7477) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.