GTF2I Antibody / General transcription factor II-I
Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE) . Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/million cells
UniProt
P78347
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the GTF2I antibody.
Clonality
Monoclonal
Isotype
IgG2b
Clone
PCRP-GTF2I-1A7
Applications
FACS
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the GTF2I antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This GTF2I antibody is available for research use only.
Storage Conditions
Aliquot the GTF2I antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the GTF2I antibody should be determined by the researcher.
Location
Nucleus
Image Legend
Frequently Asked Questions
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