ZSCAN12 Antibody
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Belonging to the Kruppel C2H2-type zinc-finger protein family, ZFP96 (zinc finger protein 96 homolog), also known as ZSCAN12 (zinc finger and SCAN domain-containing protein 12) and zinc finger protein 305, is a 604 amino acid nuclear protein that contains one SCAN box domain and 11 C2H2-type zinc fingers. ZFP96 is upregulated by 8-fold from day 13 of pregnancy to day 1 post-partum, suggesting that ZFP96 functions as a transcription factor by switching off pro-survival genes and/or upregulating pro-apoptotic genes of the corpus luteum.
Product Specifications
UniProt
O43309
Host
Mouse
Immunogen
A recombinant partial protein sequence (within amino acids 37-132) from the human protein was used as the immunogen for the ZSCAN12 antibody.
Clonality
Monoclonal
Isotype
IgG2b
Applications
FACS, IF
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the ZSCAN12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ZSCAN12 antibody is available for research use only.
CAS Number
9007-83-4
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