Octamer-binding protein 4 Antibody / OCT4
OCT4 (Octamer-binding protein 4) is a member of the POU family of transcription factors, involved in the regulation of pluripotency during normal development and is detectable in embryonic stem and germ cells. OCT4 is a key regulator of self-renewal in embryonic stem cells; its expression is potentially correlated with tumorigenesis and can affect tumor recurrence or resistance to therapies. OCT4 is expressed in undifferentiated pluripotent cells, germ cells in ovary and testes. OCT4 Ab is useful in the identification of primary as well as metastatic germ cell tumors.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Q01860
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant fragment of the human protein was used as the immunogen for the Octamer-binding protein 4 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
OCT4/7347R
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Octamer-binding protein 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Octamer-binding protein 4 antibody is available for research use only.
Storage Conditions
Aliquot the Octamer-binding protein 4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the Octamer-binding protein 4 antibody should be determined by the researcher.
Location
Nucleus
Image Legend
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