STING Antibody / MITA / ERIS / TMEM17
TMEM173 (transmembrane protein 173), also called MITA, ERIS and STING1, is a 379 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Q86WV6
Host
Mouse
Reactivity
Human
Immunogen
A recombinant partial protein sequence (within amino acids 190-290) from the human protein was used as the immunogen for the STING antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
STING1/7438
Applications
WB, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the STING antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This STING antibody is available for research use only.
Storage Conditions
Aliquot the STING antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the STING antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Western blot testing of human HDLM-2 cell lysate with STING antibody (clone STING1/7438) . Predicted molecular weight ~42 kDa.
Documents
Explore Other Products
Browse additional items from our catalog
SFN, CT (SFN, HME1, 14-3-3 protein sigma, Epithelial cell marker protein 1, Stratifin) (AP)
SFN, CT (SFN, HME1, 14-3-3 protein sigma, Epithelial cell marker protein 1, Stratifin) (AP)
TIPRL (NM_152902) Human Tagged ORF Clone Lentiviral Particle
