I-FABP Antibody / FABP2

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

P12104

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full length human FABP2 protein was used as the immunogen for the I-FABP antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

FABP2/7670

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the I-FABP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This I-FABP antibody is available for research use only.

Storage Conditions

Aliquot the I-FABP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the I-FABP antibody should be determined by the researcher.

Location

Cytoplasm

Image Legend

IHC staining of FFPE human small intestine tissue with I-FABP antibody (clone FABP2/7670) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.