TCF1 alpha Antibody / T cell specific transcription factor 1 alpha / LEF1
Lymphoid Enhancing Factor 1 (LEF1), also called TCF1 alpha, is a transcription factor that belongs to the TCF/LEF family. LEF1 participates as a regulator in Wnt signaling pathways. LEF1 is an important factor in lymphopoiesis and is expressed normally in T and pro-B cells but not expressed in mature B cells. Anti-LEF1 may be used as an aid for differentiation of chronic lymphocytic leukemia/small lymphocytic lymphoma from other small B cell lymphomas.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Q9UJU2
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment of human LEF1 protein was used as the immunogen for the TCF1 alpha antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
LEF1/6764
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the TCF1 alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TCF1 alpha antibody is available for research use only.
Storage Conditions
Aliquot the TCF1 alpha antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the TCF1 alpha antibody should be determined by the researcher.
Location
Nucleus
Image Legend
Frequently Asked Questions
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