FOXL2 Antibody / Forkhead box protein L2

FOXL2 is a critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. It prevents trans-differentiation of ovary to testis through transcriptional repression of the sertoli cell-promoting gene SOX9. FOXL2 is mainly expressed in ovary, parathyroid gland and sex cord-stromal tumors. FOXL2 is generally used for diagnosis of sex cord-stromal tumors with Inhibin, Calretinin and SF-1.

Product Specifications

CAS Number

9007-83-4

Specifications

ELISA (Order BSA-free format for coating), Flow cytometry: 1-2ug/million cells

UniProt

P58012

Host

Mouse

Reactivity

Human

Immunogen

The protein domain of FOXL2 protein was used as the immunogen for the FOXL2 antibody.

Clonality

Monoclonal

Isotype

IgG2c

Clone

PCRP-FOXL2-1B4

Applications

ELISA, FACS

Purity

Protein A/G affinity

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Aliquot the FOXL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This FOXL2 antibody is available for research use only.

Storage Conditions

Aliquot the FOXL2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the FOXL2 antibody should be determined by the researcher.

Location

Nucleus

Image Legend

Flow cytometry testing of PFA-fixed human HeLa cells with FOXL2 antibody (clone PCRP-FOXL2-1B4) followed by goat anti-mouse IgG-CF488 (blue), Red = unstained cells.