FOXL2 Antibody / Forkhead box protein L2
FOXL2 is a critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. It prevents trans-differentiation of ovary to testis through transcriptional repression of the sertoli cell-promoting gene SOX9. FOXL2 is mainly expressed in ovary, parathyroid gland and sex cord-stromal tumors. FOXL2 is generally used for diagnosis of sex cord-stromal tumors with Inhibin, Calretinin and SF-1.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (Order BSA-free format for coating), Flow cytometry: 1-2ug/million cells
UniProt
P58012
Host
Mouse
Reactivity
Human
Immunogen
The protein domain of FOXL2 protein was used as the immunogen for the FOXL2 antibody.
Clonality
Monoclonal
Isotype
IgG2c
Clone
PCRP-FOXL2-1B4
Applications
ELISA, FACS
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the FOXL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This FOXL2 antibody is available for research use only.
Storage Conditions
Aliquot the FOXL2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the FOXL2 antibody should be determined by the researcher.
Location
Nucleus
Image Legend
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