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PSAP Antibody / ACP3 / Prostate Specific Acid Phosphatase

Prostatic Acid Phosphatase (PSAP or PAP) is a member of the histidine acid phosphatase family. It is a non-specific phosphatase that is capable of dephosphorylating tyrosine residues as well as phospholipids under mildly acidic conditions. Prostatic specific acid phosphatase (PSAP) is involved in prostate epithelial differentiation. It is highly expressed in prostate, primary and metastatic carcinoma of the prostate. This marker may be helpful in pinpointing the site of origin in cases of metastatic carcinoma of the prostate, and is considered a more sensitive marker than PSA.

Product Specifications

CAS Number

9000-83-3

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

P15309

Host

Rabbit

Reactivity

Human

Immunogen

A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the PSAP antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG κ

Clone

ACPP/8409R

Type

Recombinant

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Aliquot the PSAP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PSAP antibody is available for research use only.

Storage Conditions

Aliquot the PSAP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the PSAP antibody should be determined by the researcher.

Location

Cytoplasm

Image Legend

IHC staining of FFPE human prostate carcinoma tissue with PSAP antibody (clone ACPP/8409R) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

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