CSTA Antibody / Cystatin A
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P01040
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment of human protein (around aa 1-98) was used as the immunogen for the CSTA antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG2b κ
Clone
RCSTA/8995
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the CSTA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CSTA antibody is available for research use only.
Storage Conditions
Aliquot the CSTA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the CSTA antibody should be determined by the researcher.
Location
Cell Surface, Cytoplasm, Nucleus
Image Legend
SDS-PAGE analysis of purified, BSA-free CSTA antibody (clone rCSTA/8995) as confirmation of integrity and purity.
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