H-FABP Antibody / Heart Fatty Acid Binding Protein / FABP3
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Western blot: 2-4 µg/mL
UniProt
P05413
Host
Mouse
Reactivity
Human
Immunogen
A recombinant partial protein sequence (within amino acids 1-127) from the human protein was used as the immunogen for the H-FABP antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RFABP3/8534
Type
Recombinant
Applications
IHC-P, WB
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the H-FABP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This H-FABP antibody is available for research use only.
Storage Conditions
Aliquot the H-FABP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the H-FABP antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Western blot testing of different lots of human heart lysate with H-FABP antibody. Predicted molecular weight ~14 kDa.
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