LAMP5 Antibody / Lysosome-Associated Membrane Glycoprotein 5

Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-5, also known as C20orf103, is a 280 amino acid protein that belongs to the LAMP family and is mainly found in cytoplasmic vesicles of the neuronal cell body. LAMP-5 is up-regulated upon CpG activation and down-regulated up Toll-like receptor (TLR) ligands.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

Q9UJQ1

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full-length human LAMP5 protein was used as the immunogen for the LAMP5 antibody.

Clonality

Monoclonal

Isotype

IgG2 κ

Clone

LAMP5/7642

Applications

WB, IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the LAMP5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This LAMP5 antibody is available for research use only.

Storage Conditions

Aliquot the LAMP5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the LAMP5 antibody should be determined by the researcher.

Location

Cell Surface, Lysosome

Image Legend

Western blot testing of human U937 cell lysate with LAMP5 antibody (clone LAMP5/7642) . Predicted molecular weight ~31 kDa, but may be observed at higher molecular weights due to glycosylation.