KCNJ6 Antibody / GIRK2
This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015]
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P48051
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment of human protein was used as the immunogen for the KCNJ6 antibody.
Clonality
Monoclonal
Isotype
IgG2 κ
Clone
KCNJ6/7557
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the KCNJ6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This KCNJ6 antibody is available for research use only.
Storage Conditions
Aliquot the KCNJ6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the KCNJ6 antibody should be determined by the researcher.
Location
Membrane
Image Legend
Frequently Asked Questions
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