S100 calcium binding protein A11 Antibody / S100A11
S100A11 is a Ca2+-binding protein of the S100 family. The proteins comprising the S-100 protein family have two EF-hand structures per molecule of protein. Expression of these family members occurs primarily in neurons or retinal photoreceptor cells, and may also be involved in a wide variety of cellular functions including cell growth, cell-cell communication, energy metabolism and intracellular signal transduction. They have also been linked to various pathologies, including Alzheimer s disease, schizophrenia and cancer. S100A11 is highly expressed in lung tissue and is also expressed in kidney, liver, brain, heart and smooth muscle. It is an important androgen-responsive protein produced by Sertoli cells and might play a role in spermatogenesis regulation.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P31949
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the S100 calcium binding protein A11 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
S100A11/7394
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the S100 calcium binding protein A11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This S100 calcium binding protein A11 antibody is available for research use only.
Storage Conditions
Aliquot the S100 calcium binding protein A11 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the S100 calcium binding protein A11 antibody should be determined by the researcher.
Location
Cytoplasm, Nucleus
Image Legend
Documents
Frequently Asked Questions
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