S100 Calcium Binding Protein A2 Antibody / S100A2
S100A2 belongs to the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A2 may function as a modulator against excess calcium accumulation in normal human mammary epithelial cells and also have a role in suppressing tumor cell growth. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. Cytoplasmic overexpression may also be of prognostic significance when observed in oral cancer patients, and the S100A2 has also been identified as significantly down regulated in gastric cancer.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (Order BSA-free format for coating)
UniProt
P29034
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the S100 Calcium Binding Protein A2 antibody.
Clonality
Monoclonal
Isotype
IgG2b
Clone
RS100A2/6482
Applications
ELISA
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the S100 Calcium Binding Protein A2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This S100 Calcium Binding Protein A2 antibody is available for research use only.
Storage Conditions
Aliquot the S100 Calcium Binding Protein A2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the S100 Calcium Binding Protein A2 antibody should be determined by the researcher.
Location
Nucleus, Cytoplasm
Image Legend
SDS-PAGE analysis of purified, BSA-free S100 Calcium Binding Protein A2 antibody (clone rS100A2/6482) as confirmation of integrity and purity.
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