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Stathmin 1 Antibody / STMN1 / Op18

Stathmin 1 (also called Oncoprotein 18, Op18, Prosolin and Metablastin) is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation.

Product Specifications

CAS Number

9000-83-3

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

P16949

Host

Rabbit

Reactivity

Human

Immunogen

A recombinant fragment of human STMN1 protein was used as the immunogen for the Stathmin 1 antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG κ

Clone

STMN1/8023R

Type

Recombinant

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the Stathmin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Stathmin 1 antibody is available for research use only.

Storage Conditions

Aliquot the Stathmin 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the Stathmin 1 antibody should be determined by the researcher.

Location

Cytoplasm

Image Legend

IHC staining of FFPE human tonsil tissue with Stathmin 1 antibody (clone STMN1/8023R) . Inset: PBS used in place of primary Ab (secondary Ab negative control) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

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