MCAK Antibody / Mitotic centromere associated kinesin / KIF2C
Kinesin family member 2c (KIF2C), alternately known as mitotic centromere associated kinesin (MCAK), is a member of the kinesin-like family of proteins. KIF2C is a cytoplasmic and nuclear protein, present throughout the cell cycle. KIF2C associates with the centromere early in prophase, and disassociates after telophase. KIF2C is abundant in thymus and testis, and present at lower levels in small intestine, the mucosal lining of the colon, and placenta. Human KIF2C maps to chromosome 1p34.1.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Q99661
Host
Mouse
Reactivity
Human
Immunogen
A recombinant partial protein sequence (within amino acids 500-700) from the human protein was used as the immunogen for the MCAK antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
KIF2C/6522
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the MCAK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MCAK antibody is available for research use only.
Storage Conditions
Aliquot the MCAK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the MCAK antibody should be determined by the researcher.
Location
Cytoplasm, Nucleus
Image Legend
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