L1TD1 Antibody / ECAT11

L1TD1 (LINE-1 type transposase domain containing 1), also known as ECAT11 (ES cell-associated protein 11), is an 865 amino acid protein that belongs to the transposase 22 family and is encoded by a gene that maps to human chromosome 1p31.3. Chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

Q5T7N2

Host

Mouse

Reactivity

Human

Immunogen

A recombinant fragment of human L1TD1 protein was used as the immunogen for the L1TD1 antibody.

Clonality

Monoclonal

Isotype

IgG2 κ

Clone

L1TD1/7941

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the L1TD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This L1TD1 antibody is available for research use only.

Storage Conditions

Aliquot the L1TD1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the L1TD1 antibody should be determined by the researcher.

Location

Cytoplasm, Secreted

Image Legend

IHC staining of FFPE human prostate tissue with L1TD1 antibody (clone L1TD1/7941) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.