ZNF444 Antibody / ZSCAN17
Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the Kruppel C2H2-type zinc finger protein family, ZNF444 (zinc finger protein 444), also known as EZF2 or zinc finger and SCAN domain-containing protein 17 (ZSCAN17), is a 327 amino acid transcriptional regulator. ZNF444 localizes to the nucleus and contains four C2H2-type zinc fingers and one SCAN domain. The SCAN domain is a highly conserved motif that is found near the N-terminus of a subfamily of C2H2 zinc finger proteins. The SCAN domain helps to mediate self-association or selective association with other proteins bearing the SCAN domain. Two isoforms of ZNF444 exist due to alternative splicing events.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2 µg/mL
UniProt
Q8N0Y2
Host
Mouse
Reactivity
Human
Immunogen
A recombinant partial protein sequence (within amino acids 25-105) from the human protein was used as the immunogen for the ZNF444 antibody.
Clonality
Monoclonal
Isotype
IgG2a
Clone
PCRP-ZNF444-1E11
Applications
FACS, IF
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the ZNF444 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ZNF444 antibody is available for research use only.
Storage Conditions
Aliquot the ZNF444 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the ZNF444 antibody should be determined by the researcher.
Location
Nucleus
Image Legend
Frequently Asked Questions
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