KLK7 Antibody / Kallikrein 7

KLK7/Kallikrein 7 may catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface as well as play a role in the activation of precursors to inflammatory cytokines. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

P49862

Host

Mouse

Reactivity

Human

Immunogen

A recombinant fragment of human KLK7 protein (within amino acids 1-200) was used as the immunogen for the KLK7 antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

KLK7/4691

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Aliquot the KLK7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This KLK7 antibody is available for research use only.

Storage Conditions

Aliquot the KLK7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the KLK7 antibody should be determined by the researcher.

Location

Secreted

Image Legend

Analysis of a HuProt (TM) microarray containing more than 19,000 full-length human proteins using KLK7 antibody (clone KLK7/4691) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a mAb to its intended target. A mAb is considered to specific to its intended target, if the mAb has an S-score of at least 2.5. For example, if a mAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that mAb to protein X is equal to 29.