Uroplakin 3B Antibody / UPK3B
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.
Product Specifications
CAS Number
9000-83-3
Specifications
ELISA (Order BSA-free format for coating), Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Q9BT76
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant partial protein sequence (within amino acids 100-300) from the human protein was used as the immunogen for the Uroplakin 3B antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
UPK3B/8768R
Type
Recombinant
Applications
ELISA, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the Uroplakin 3B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Uroplakin 3B antibody is available for research use only.
Storage Conditions
Aliquot the Uroplakin 3B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the Uroplakin 3B antibody should be determined by the researcher.
Location
Cell Surface
Image Legend
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
