SBSN Antibody / Suprabasin
Suprabasin (SBSN) is a 247 amino acid secreted protein that is upregulated in differentiating keratinocytes and is though to play a role in epidermal differentiation. Expressed in uterus, skin, thymus and esophagus, suprabasin is encoded by a gene that maps to human chromosome 19q13.12. Chromosome 19 consists of about 63 million bases with over 1,400 genes, making up over 2% of human genomic DNA. Chromosome 19 is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families, and Fca receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and Insulin-dependent diabetes have been linked to chromosome 19.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Q6UWP8
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment from the human protein was used as the immunogen for the SBSN antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
SBSN/7961
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the SBSN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SBSN antibody is available for research use only.
Storage Conditions
Aliquot the SBSN antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the SBSN antibody should be determined by the researcher.
Location
Cytoplasm, Secreted
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD79b (B-Cell Marker) (IGB/1844), CF640R conjugate, 0.1mg/mL
Calponin (CNN1) (N-term) Rabbit Polyclonal Antibody
