UPK3B Antibody / Uroplakin 3B
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (Order BSA-free format for coating), Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Q9BT76
Host
Mouse
Reactivity
Human
Immunogen
A recombinant partial protein sequence (within amino acids 100-300) from the human protein was used as the immunogen for the UPK3B antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
UPK3B/3270
Applications
ELISA, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the UPK3B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This UPK3B antibody is available for research use only.
Storage Conditions
Aliquot the UPK3B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the UPK3B antibody should be determined by the researcher.
Location
Cell Surface
Image Legend
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